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Linkage disequilibrium, as a nonrandom association, has been considered to be profoundly associated with recombination hot spots, quantitative characters, and complex diseases [43].
When the English, later the American, novel began in the late 17th century, it was profoundly associated with transgression.
Given that peroxynitrite (ONOO−) is profoundly associated with health and diseases, a new fluorescent probe ABT was designed and synthesized for detection of ONOO−.
The authors report that prolactin related effects were profoundly associated with increased suicide risk: amenorrhea increased the suicide risk by 64%, galactorrhea by 163% and gynecomastia by 200%.
Recent studies have revealed that a malfunction of RXRα, one of the subtypes of RXR, due to aberrant phosphorylation by the Ras/mitogen-activated protein kinase (MAPK) signaling pathway is profoundly associated with liver carcinogenesis [ 4- 9].
Strikingly, these responses were most profoundly associated with changes in expression of genes encoding the catabolic enzymes of the amino acids with only minor changes in mRNA levels of genes encoding the biosynthesis enzymes [ 19].
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In either case, inflammation profoundly associates with the TLR3 response, which includes an alteration of epigenetic status in cells that leads to innate immune activation as well as tumor regression.
"I'm not a mystic, and yet this idea of setting out on these paths which are so profoundly and durably associated with time folding back on itself... what I think I heard was owls, possibly tawnys, but there was a weird geometry to the event, these two voices that moved, and then joined, and were so human.
Previous research in our laboratory has shown that damage to the amygdala in neonatal rhesus monkeys profoundly alters behaviors associated with fear processing, while leaving many aspects of social development intact.
There has been an explosion of interest in Nav1.7 as a potential therapeutic target for novel analgesics, as mutations in SCN9A are associated with profoundly altered pain thresholds.
In burned patients, the length and magnitude of the hypermetabolic state is the highest of all patients and associated with profoundly increased morbidity and mortality.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com