Sentence examples for profoundly accelerated from inspiring English sources

We showed that a well-characterized Foxp3gfp reporter mouse, which expresses an N-terminal GFP-Foxp3 fusion protein, is a hypomorph that causes profoundly accelerated autoimmune diabetes on a NOD background.

Furthermore, downregulation of PTENP1 profoundly accelerated the proliferation of DU145 cells, with silencing of both PTEN and PTENP1 having an additive effect (Poliseno et al., 2010).

However, these 'normal' consequences are profoundly accelerated by disease pathophysiology and the use of conventional adjuvant therapy to create a 'perfect deconditioning storm', reducing either the body's ability to deliver and/or utilize O2 and substrate leading to poor VO2peak[ 9].

Seen from the region, the move will be profoundly destabilising, accelerating Japanese and South Korean efforts to build missile defences.

The chapter also describes the way structural knowledge combined with various computational tools profoundly influences and accelerates drug discovery by either de novo design of leads or the improvement of existing leads.

This movement started before the Citizens United decision, but the Roberts Supreme Courtt has accelerated the pace and thereby profoundly weakened our democracy.

If the foraging onset differences between these phenotypic groups result from proportional differences in pre-foraging task performance, this would suggest a general temporal behavioral program that can be accelerated or slowed down but not profoundly altered.

The singularity The point at which accelerating technology profoundly changes human existence.

We therefore interpret the observed gene expression pattern as accelerated stress induced premature senescence phenotype resulting from impaired oxidative phosphorylation and profoundly reduced ATP availability for critical energy-dependent cellular processes.

Events accelerated.

He did not grasp how profoundly the transformation of the Republican Party into a disciplined, nearly monolithic agent of radical reaction and ruthless obstruction a transformation that has only accelerated since that day had changed things already.