The trivial and the profound, the vital and the poisonous, the true and the false it is impossible to tell the difference now, and meaningless to try.
Alterations in these critical chromatin remodelers have profound effects on vital processes, such as differentiation, cell proliferation, and metastasis.
Questions as vital and profound as those could only possibly be answered by people with the insight that positions of power and importance afford, so I called up Unesco's assistant director-general, Hans d'Orville, in an attempt to understand what the world is going to look like in 2022.
Thus, mutations in the PRPS1 can have a profound impact on several vital cell processes, such as nucleic acid synthesis, energy metabolism, and cellular signaling.
In a search for a non-toxic nicotinic agonist, we have identified rapid and profound effects on keratinocyte vital functions of the novel non-canonical ligands of nAChRs secreted mammalian Ly-6/urokinase-type plasminogen activator receptor-related protein (SLURP -1 and -2 that are produced by SLURP -1ls to andment the physiologic effects of ACh at nAChRs.
At the same time, a growing body of scientific research is emerging to suggest that low-level exposure to some of these PCBs may have potentially profound effects on biological mechanisms vital to healthy development.
This is a vital, mesmerising work, at once profound, funny and full of the many ways we hurt each other and ourselves.
Buddy Rich called Shaughnessy "one of my all-time favorite drummers" — high praise from a musician whose dynamic, virtuosic style contrasted with Shaughnessy's profound belief in the drummer as a vital member of a band's rhythm section.
In South Africa especially, scale up of donor breastmilk banks would have a profound impact on breastfeeding promotion which is vital in order to improve infant survival rates.
Grothendieck's discoveries in the 1960s on the profound relationship between spaces and numbers are still vital to modern genetics, robotics and cryptography.
