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"profound relationship" is a correct and usable phrase in written English.
It can be used to describe a close, meaningful, and intimate connection between two people. For example, "John and Mary built a profound relationship over the past four years."
Exact(46)
Gordon's profound relationship with this place, and his quicksilver mind, have had imaginative consequences.
Scholem's most profound relationship was, perhaps, with his mother, and their correspondence here is endlessly touching.
When the war broke out, his already profound relationship with Syrians of all affiliations deepened further.
We need to look beyond cognitive science to cultivate a truly profound relationship to the world we live in.
The intellectual and practical lesson is that there is a profound relationship between the public and private.
In my view there is a profound relationship between those who wish to protect intellectual property and those who wish to protect privacy.
Similar(14)
Yet even with such limited materials, players were able to build profound relationships, even if they were fleeting and ethereal.
He never told a soul, but believes now that the trauma stopped him from developing "profound" relationships with men.
But that ignores the more interesting story of the complicated and profound relationships among the main characters.
But the secret of his creative longevity was to embrace the new, as well as establishing profound relationships with designers, working in their individual cultures.
Few take the time to ponder those profound relationships, and perhaps are told, as were we, to close the shade and let others sleep.
More suggestions(15)
serious relationship
fundamental relationship
severe relationship
great relationship
in depth relationship
profound relations
profound relationships
profound links
deepest relationship
deep rooted relationship
underlying relationship
profound connections
deepening relationship
grave relationship
profound interactions
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com