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To place an emphasis on profound relations among airline schedule planning problems and to mitigate the effect of unexpected delays, we integrate schedule design, fleet assignment and aircraft routing problems within a daily planning horizon while passengers' connection service levels are ensured via chance constraints.
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The univariate Cox analysis showed a profound relation of high PRMT1-v1 expression and both DFS and OS of patients.
"Self-actualizing people have deeper and more profound interpersonal relations than any other adults They are capable of more fusion, greater love, more perfect identification, more obliteration of the ego boundaries than other people would consider possible.
Marcel Proust, whom she considers "in some ways the most profound object-relations psychoanalyst of all," provides her title, in his observation that love "produces real geological upheavals of thought".
That meeting led to a profound change in relations between the two countries.
In the early aughts, she studied the profound shift in relations between the Hutus and the Tutsis at the time of the Rwandan genocide.
The decision is likely to have profound implications for relations between the US and Egypt after decades of close ties that have served as a bulwark of security and stability in the Middle East.
Decolonization nonetheless had a profound effect on international relations through the medium of the UN.
Foreign-policy strategists built in economics only to the extent that it could pay the bills.And yet shifts in economic relations have profound effects on strategic relations, too.
As these two projects -- Europe's rapid reaction force, America's missile shield -- confront each other, a profound change in transatlantic relations seems clear.
The effort is being spurred by the profound changes in public relations since the last time the organization updated its definition, in 1982.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com