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Discover Ludwig"profound negative" is a correct and usable phrase in written English.
You can use it when referring to something that has a deeper level of bad or negative consequences than a usual negative outcome. For example, "The environmental impact of this development has profound negative consequences for the surrounding area."
Exact(60)
"American support for Palestinian statehood is therefore crucial, and a veto will have profound negative consequences.
The problem with this theory was that ACEs had a profound negative effect on adult health even when those behaviors weren't evident.
We also need to consider the suffering that is being endured by these high levels of joblessness, including the profound negative effect on the families of the unemployed.
The AIDS epidemic has had less overall economic effect than earlier feared, the report said, but is having profound negative effects in industries and agriculture in high-prevalence countries.
The report's recommendations include: The government should take action to discourage schools from setting children by ability, particularly at primary level, because of evidence that it could have a profound negative impact on pupils' future social mobility.
"The global credit crisis has had a profound negative impact on what was already a weakening and very fragile global economy," Jeffrey M. Fettig, the chairman and chief executive, said in a statement.
"We believe that the Arctic refuge should be preserved and that the budgetary effects of oil leases in the refuge are incidental when considering the profound negative impact of drilling in the Arctic refuge".
Treating APIs as copyrightable would have a profound negative impact on interoperability, and, therefore, innovation.
Lymphedema following treatment for breast cancer can be an irreversible condition with a profound negative impact on quality of life.
Urbanization and agricultural intensification resulting in habitat loss is having a profound negative effect on grassland and farmland birds worldwide.
Furthermore, some common forest management practices can have a profound negative effect on cavity quantity and quality.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com