Sentence examples for profound modifications from inspiring English sources

There, he writes that "even in those countries which give legal sanction to the festive character of Sunday, changes in socioeconomic conditions have often led to profound modifications of social behavior and hence of the character of Sunday".

After the colonies passed to the British crown, the old law underwent profound modifications, partly because of changed social and economic conditions and partly because of the incursion of rules and institutions derived from English common law.

Sexuality is one of the aspects that undergoes the most profound modifications.

In addition, the pattern of ecosystem demands shows a levelling of rural urban gradients, reflecting profound modifications of traditional rural urban relationships.

We use daily data from 2010 to 2015, a period with profound modifications in the German electricity market, the most notable being the rapid integration of photovoltaic and wind power sources, as well as the phasing out of nuclear energy.

However, further analyses of data suggest that the ancestral/innate compartment of immune system (e.g., MCs, NKs, DCs, MΦs) is relatively preserved in older individuals compared with the more acquired sophisticated and complicated adaptive immune cells (e.g., T and B cells, Treg, Th1/Th2, CD4+/CD8+) that undergo profound modifications throughout life [4, 6, 11, 13 15, 23, 58 61, 66 72].

Other kinds have undergone profound modification for natatorial (swimming) locomotion for life at sea.

The object we are accustomed to calling a book is undergoing a profound modification as it is stripped of its physical shell.

A whole group of Philippine roaches of the genus Prosoplecta mimics these beetles, having undergone profound modification to achieve the similarity.

"I had these big boxes — shoeboxes — full of clippings, and, like that, I saw that something was happening, a profound modification of our society, and that no one was noticing, or they were noticing but not really saying anything about it".

The next generation of polymer conjugation technology enables more complex and profound modification of cytokine activity.