Sentence examples for profound mark from inspiring English sources

His three years there had left a profound mark.

Nicholas's short but eventful reign left a profound mark on the medieval church and papacy.

For the human beings who passed through it, the stoneyard left a profound mark.

The pontificate of John Paul II, one of the longest in history, left a profound mark on the church and the papacy.

Far from it: in the second quarter of this year they put almost $7 billion into Silicon Valley technology companies a new high.A softer touchMost agree that the Internet boom has left a profound mark on the Valley.

The country was ready for Ehrlich's message when he published "The Population Bomb" in 1968, but his tremendous success in turn left a profound mark on public thinking about environmental problems.

Their duration alone is exceptional, as is their emphasis on the physical struggle, the passionate and uninhibited athleticism of sex, the profound marking of the characters' souls by their sexual relationship.

A key preclinical study which laid the groundwork for the clinical development of sipuleucel-T demonstrated that mice immunised with APCs incubated with a fusion protein of rat PAP and rat GM-CSF developed profound prostatitis (marked lymphocyte infiltrate), indicating that this approach could break tolerance to the self-antigen [ 42, 43].

None of the people I spoke to had any doubt that humans were leaving a profound and lasting mark on our planet's geology.

Ultimately, she leaves a profound and lasting mark on TV news for excelling at both hard and pop-culture news.

For most of us, the home is the focus of religious life and worship and the location for the performance of those profound rituals that mark the life-stages: birth, marriage, and death.