Sentence examples for profound infiltration from inspiring English sources

Major differences to classical EAE models were seen in the composition of inflammatory infiltrates, being dominated by B-cells, infiltration of IgM positive plasma cells, profound infiltration of the tissue by CD8+ T-lymphocytes and a nearly complete absence of CD4+ T-cells.

The incident has also served as a reminder of the profound infiltration of organized crime into seemingly all aspects of Mexican society, from politics to the press, especially in the violence-weary state of Michoacán.

The rheumatoid synovium is an area of intense immunological activity [3], [4] with a profound infiltration of inflammatory cells, including mononuclear cells and lymphocytes, which occasionally form secondary lymphoid structures [5].

There was a more profound infiltration of CD8+ T cells into the tumour treated with B7-H3 blocomparedmpared with controls (anti-B7-H3 mAb, n=5, 134.2±11.2; control, n=5, 50.5±11.2, P<0.001).

T-cell acute lymphoblastic leukemia (T-ALL), which accounts for approximately 15% of childhood ALL and 25% of adult ALL cases 1, is characterized by a profound infiltration of the bone marrow with clonally rearranged T-cell receptor (TCR) 2 lymphoblasts 3 that stain positively for TdT and express CD1a, CD2, CD3, CD5, CD7, and CD8 1.

Intranasal instillation of bacteria caused profound neutrophil infiltration into the lung alveoli as well as a significant increase in the levels of pro-inflammatory mediators (i.e. TNFα and IL-1α).

Similarly, treatment with NTHi lysate induces no systemic leukocytosis (data not shown), despite the profound cellular infiltration induced in the lungs.

The molecular identification was compatible with the subsequent histologic finding of profound macrophage infiltration without granuloma and the presence of Ziehl-Neelsen positive bacilli.

Intranasal instillation of bacteria caused profound neutrophil infiltration into the lung alveoli as well as a significant increase in the levels of proinflammatory mediators (that is, TNFα and IL-1α).

Inflammatory infiltrates were observed within the proliferating and thickened synovial lining layer with profound lymphocytic and granulocyte infiltration as well as the presence of small vessels (L. Kenner, unpublished data).

Characteristic for KS are proliferating spindle-shaped cells, inflammatory cell infiltration, and profound angiogenesis.