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The phrase 'profound examination' is correct and usable in written English.
This phrase can be used to describe any in-depth or detailed study or analysis. For example, you could say: "The professor conducted a profound examination of the medical records to identify any potential risk factors."
Exact(11)
It is a profound examination of memory and guilt, of the way we recall past trauma en masse.
Why couldn't a more profound examination of Lincoln be at the heart of the educational program instead of platitudes?
In 2002 the UN published a profound examination of Arab human development - written by Arab experts - and demonstrated that the region was the hungriest in the world for democracy.
Digging to America (2006), in which Iranian-American and all-American families each adopt a Korean child, is a profound examination of immigration and assimilation and what it means to be American, which has become ever more resonant with the election of a Kenyan-American president accused by his opponents of being a secret Muslim.
It seems clear that the Muslim Brotherhood and their supporters would have lost the referendum; and they would have had to engage in a profound examination of what it was about their vision and their practice that was so unsuited to Egypt.
(I owe this observation to Roderick Tweedy's remarkable The God of the Left Hemisphere (2012), and through that to Iain McGilchrist's The Master and His Emissary (2009), a profound examination of the differences between the left hemisphere of the brain and the right).
Similar(49)
But whereas Cosi ranks among the most profound examinations of the human psyche, La Grotta di Trofonio may best be described as an entertaining phantasmagoria, albeit a superbly composed one, in which Salieri reveals both an affecting lyrical sensibility and, on occasion, a fine ear for parody.
But you then you had profound examinations of the zeitgeist beginning with Max Weber's The Protestant Ethic and the Spirit of Capitalism, Tonnies Communityy and Society, George Simmel's essay, "The Metropolis and Mental Life" and in the past century two brilliant tomes, David Reisman's The Lonely Crowd and Erving Goffman's The Presentation of Self in Everyday Life.
If discourse analytical methods should be integrated in future research, a more profound critical examination of the underlying principles and assumptions of a combined approach are necessary.
Profound histopathological examination was performed to determine the effect of RFITT on tonsillar architecture.
Hence we collected tonsillectomy specimens after bipolar RFITT and performed profound histopathological examination comparing these cases to standard tonsillectomy ones.
More suggestions(15)
considerable examination
profound consideration
profound review
severe examination
tremendous examination
serious examination
grave examination
great examination
heartfelt examination
profound considering
root and branch examination
in depth examination
deepest examination
thoroughgoing examination
far reaching examination
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com