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Monsignor Cassato emphasized to his parishioners that the act of lifting is a profound display of faith, powered not by mere muscle but by the Holy Spirit.
Paco recommends: "In addition to a profound display of knowledge about the human condition, Stoner is an irresistible exhibition of command of the Art of Literature resulting into one of last Century's top masterpieces.
Yet the conspiracy theorist in a profound display of ignorance will convince him/herself that such vital findings are absolutely unimportant and rage on with their own lunacy.
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The essential role that Cxs play in hearing is further recognized by profound deafness displayed in Cx30 null and conditional Cx26 null mouse models [7], [8].
The identification of parasite targets for drug development is a priority and parasitic protein kinases suggest themselves as suitable targets as many display profound structural and functional divergences from their host counterparts.
While we are not the first to consider how displays might be optimized for older users (see Kline (1994) for a discussion of potential optimizations and Adams and Hoffman (1994)), there have been profound changes in display technology since then, how designers intend them to be used and how users, in fact, use them, and our results speak to some of these newer user behaviors.
Indeed, DAT-KO mice display profound alterations in serotonin homeostasis that may underlie the changes in baseline neuron-oscillatory properties presented here [25].
Mice deficient in either CXCL12 or its seven-transmembrane G protein coupled receptor (GPCR) CXCR4 die perinatally and display profound defects in the hematopoietic system [2], [3].
This is because spectrum diseases in psychiatry, such as schizophrenia or depression, display profound heterogeneity with regard to the underlying pathophysiological mechanisms, requiring the development of models that can infer subject-specific mechanisms from neurophysiological and/or behavioural data [35].
In Drosophila, mutants carrying a deletion of the Mnn1 gene are hypersensitive to several mutagens or gamma irradiation and display profound defects in the stress response [5], [16], [21].
It now remains to determine whether p53 could modify the post-transcriptional steps of ribosome biogenesis, in particular the level of rRNA methylation Altogether our results show that breast cancer cells with enhanced aggressivity display profound alterations in ribosome biogenesis resulting in the modification of translational initiation ability of the ribosomes.
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Justyna Jupowicz-Kozak
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