Sentence examples for profound deterioration from inspiring English sources
While high-fat diet stimulated β cell autophagy in control mice, it induced profound deterioration of glucose tolerance in autophagy-deficient mutants, partly because of the lack of compensatory increase in β cell mass.
Even tragi-comic television shows such as the Netflix original series, Orange Is the New Black have depicted the profound deterioration that being placed in conditions of isolated confinement renders.
It is now quite clear that exposure to bullying can lead to a profound deterioration of the person's psychological health, mainly via stress experiences [ 13].
Seeing that exposure to bullying can lead to a profound deterioration of the victim's psychological health mainly via the experience of stress [ 13], the same mechanism seems to also influence physical health, specifically MSDs.
Although the profound deterioration of all children with this condition makes it difficult to limit therapy, it is important for the patient, physician and the health care system to have proper data validating treatment decisions.
The concept of acute-on-chronic liver failure (ACLF) was introduced recently to describe a subset of patients with chronic liver disease presenting with profound deterioration of liver function and rapidly evolving multi-organ failure.
As in other tissues, the diabetic metabolism leads to profound deteriorations in the oral cavity that may predispose for oral leukoplakia (9).
MPSIIIA is due to deficiency of the heparan N-sulfatase enzyme, and is characterized by profound mental deterioration, hyperactivity, and relatively mild somatic manifestations.
Thus the data provided here exclude profound hemodynamic deterioration as the underlying mechanism for the devastating outcome of the HVT 1 1 group.
Subjects are afflicted with a variety of disconcerting symptoms, including profound cachexia and deterioration in performance status (PS), even when their tumour burden is low [ 2, 3].
Skeletal muscle undergoes a profound age-related deterioration called sarcopenia, which is characterized by a marked decline in muscle mass and function.
