Recent experimental work on chordates has highlighted a profound bias caused by decay, resulting in the erroneous interpretation of badly decayed specimens as primitive members of a clade (stemward slippage).
Les Black: Professor of sociology, Goldsmiths, University of London "'Ghost Town' captures in minimal detail, but to profound effect, the urban decay of Britain in 1981.
However, very low concentrations of Na+ cause profound differences in the decay and rise time of photocycle intermediates, consistent with a switch from a "Na+-independent" to a "Na+-dependent" photocycle (or photocycle branch) at ∼60 μM Na+.
In the proband, we provide evidence of abolished NOTCH3 expression, due to RNA decay, resulting in profound deregulation of NOTCH3 target genes.
The particles given off during the decay process are part of a profound fundamental change in the nucleus.
How, then, has Detroit achieved the profound distinction as the epitome of American decay and unrelenting collapse, failure, and ruin?
We report that DUX4-triggered proteolytic degradation of UPF1, a central component of the nonsense-mediated decay (NMD) machinery, is associated with profound NMD inhibition, resulting in global accumulation of RNAs normally degraded as NMD substrates.
Rendered symmetrically like rorschach tests, Garcia's most recent images explore the natural cycles of decay and rebirth, as well as the profound mysteries behind unconscious manifestations.
Splicing-dependent deposition of the EJC plays a profound role in mRNA metabolism, regulating nuclear export, nonsense-mediated decay, efficiency of translation, and RNA localization (Hachet and Ephrussi 2004; Ghosh et al. 2012, 2014; Popp and Maquat 2014).
The pronounced differences in decay kinetics determined for α1β2γ2 and α3β2γ2 receptors indicate profound differences in the gating properties of these two receptor subtypes.
