It was simply that autism, a profound neurological condition affecting as many as one in 150 children, had become a part of my own life.
He thought it was the result of a concussive martial arts injury I had experienced a few years earlier and called my condition "profound, progressive and irreversible".
Increase in bacterial colony forming units (CFU) coupled with gross histopathology of kidney in arsenic exposed-bacteria challenged fish suggested profound immuno-compromised condition.
Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is an effective technique to rescue patients with refractory cardiogenic shock (CS), which might benefit to some patients with refractory CS after CA. However, usefulness of VA-ECMO in refractory post-cardiac arrest syndrome is debated because most patients have profound vasoplegia, a condition in which VA-ECMO is ineffective.
They panic that it is a profound and prolonged condition and are not aware that it can be effectively treated and that reasonable adjustments can be easily made that will improve occupational functioning.
This strong attachment to Catholic values has often been seen as one of the important reasons for a delayed diffusion of new family behaviors such as cohabitation or non-marital childbearing and a profound tendency to condition childbearing on an entry to marriage (De Rose et al. 2008; Kotowska et al. 2008).
Under some conditions, profound changes in surface morphology may lead to no measurable alteration in the infrared spectrum, while, under other circumstances, variations of only a few percent in the occupancy of different adsorption sites may alter spectra quite massively.
Therefore, dependent on the region in the gene where the probes are binding to measure expression of a reference gene, profound differences among conditions can be the result of alternatively spliced or terminated transcript variants.
In this paper, the reference gene status of ribosomal protein genes was questioned by showing that as a group they were more highly expressed in tissues with faster cell division and by showing more profound differences between conditions on the basis of tissue-specific isoforms or transcript variants.
This effect was most profound in hypoxic conditions and was, in fact, greater than that in hypoxaemia alone.
