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This represents a profound compromise, one taken up by the other women living in the half-wrecked but nonetheless habitable apartment building where much of the film's action takes place.
One study showed that individuals with diabetic foot ulcers experienced profound compromise of physical quality of life, which was worse in those with unhealed ulcers.
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Could it really be that Friedman has failed to notice that many Democratic issue positions in precisely those areas in which Friedman calls for a Grand Bargain -- such as Obamacare and Cap and Trade -- already reflect profound ideological compromise with "free-market" conservative solutions to pressing problems?
We find it unlikely that the possible endotoxaemia was severe since profound cardiovascular compromise was not observed.
In his profound study On Compromise and Rotten Compromises, the Israeli philosopher Avishai Margalit distinguishes between regimes that rest on cruelty and humiliation, as many have done throughout history, and those that go further by excluding some human beings altogether from moral concern.
For the pastors who objected to Pastor Benke's participation in the service, the issue is profound: once a faith compromises on one principle, its whole architecture is threatened.
This dysfunction may result in acute hemodynamic compromise leading to profound hypoperfusion that adds additional ischemic injury to vital organs, and has been associated with early death after initial successful resuscitation [ 15].
Compromised health in childhood has profound effects on health in adulthood, as well as on the development of the cognitive skills necessary for reasoning and self-determination.
The Founding Fathers' great social experiment--to create a government based on reason and compromise--has been a profound success and given us the many freedoms we enjoy today.
Exposure to JP-8 can compromise the immune system, causing alterations so profound, the study goes on to say, that they can result in various forms of cancer.
The loss of NO after myocardial I-R therefore poses profound deleterious effects on the coronary vasculature that further compromises myocardial function.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com