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In the 1980s, academics believed that technology would introduce profound changes for humankind, especially women.
The push into the Industrial Internet is likely to have profound changes for G.E. as well.
This led to profound changes for some of London's most venerable galleries.
But others see the administration heading for an immense failure, one that would mean profound changes for the worse.
Brexit presents profound changes for British businesses: from how they trade, to how they are regulated and how they employ people.
Brexit implies profound changes for British businesses: from how they trade, to how they are regulated and how they employ people.
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The most profound change for Baltimore will be that the Ravens will now be the hunted rather than the hunters.
Yet, even as the intervening period has brought profound change for the United States and its role in the world, have we learned the lessons of that disastrous period?
The Riehls' 1957 Chrysler was built in an era of profound change for the American auto industry, its confidence finally rebounding after World War II.
"I honestly think we're seeing a more profound change, for mapmaking, than the switch from manuscript to print in the Renaissance," says the University of London cartographic historian Jerry Brotton.
This idea, labeled "the third cloud" by David P. Reed of MIT, underscores the most profound change for smartphones currently coming to the market — namely, that they need not communicate with the carrier at all.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com