Sentence examples for profound and permanent from inspiring English sources

The centuries between the Han and the Tang thus had a profound and permanent impact on the Chinese world.

For actively dying patients, even a temporary pause in the law could have a profound — and permanent — effect, Shavelson added.

She said it with such certainty that it was clear she considered this not a temporary lapse in my fashion sense, but a profound and permanent character flaw.

And a vote to leave is a vote for a profound and permanent loss the whole country would feel, whether through lost jobs or lost generations.

BCG also changed glycolysis in vitro with increased glucose uptake of infected monocytes, a process similar but not identical to the Warburg effect.40,52 Before this 8-year long trial, it was not appreciated that infection with mycobacterium as a avirulent strain could have such a profound and permanent therapeutic effect on a systemic basis.

Young children are particularly vulnerable to the toxic effects of lead and can suffer profound and permanent adverse health effects; particularly, it causes moderated development of the brain, learning issues, debilitated hearing, conduct issues (for example, hyperactivity), nerve and/or mind harm, extreme lethargies, and even demise.

But a yearlong examination of the effects of this very new technology on a very old social institution shows that they are systemic, profound, complex and permanent.

You can expect challenges, epiphanies, and profound permanent shifts that will rock your world from the ground up.

Scientific evidence supporting the common notion that hypoglycemia is responsible for an increased mortality and profound permanent neurocognitive dysfunction rather than it being just a marker of severity of illness is poor and controversial, however.

From a clinical standpoint, one cannot argue with the notion that this is a most unfortunate and gut-wrenching situation; Harry's failed suicide attempt led to horrific clinical consequences of overwhelming and permanent disability, profound disfigurement, and complete and utter dependency on others and society in general for all aspects of his care.

Hip fractures are associated with a 30% mortality rate at 1 year [ 8] and profound temporary and sometimes permanent impairment of independence and quality of life [ 9, 10].