Sentence examples similar to profound alteration from from inspiring English sources

A major finding in our studies is the unexpected profound alteration of signaling pathways in monocytes from patients treated with tremelimumab.

But it's also about a profound alteration that these scientists wrought in the way we look at reality.

But only one book had such a decisive impact that I can date to it a profound alteration in my worldview and even behaviour.

Paget Disease of the bone is a metabolic disorder which leads to a profound alteration of the bone's architecture.

So converting a virus that cannot "fly" as a means of transmission into one that can is, in fact, a profound alteration in biology.

Therefore, the antimalarial activity of MeSter would directly depend on a profound alteration of membrane fluidity.

Of the three HGT mechanisms, transduction involving bacteriophage-mediated DNA transfer often provides the profound alteration in host bacterial genomes.

When miR-221 and miR-222 were expressed in myotubes undergoing maturation, a profound alteration of myofibrillar organization was observed.

During diabetes a profound alteration in the concentration and composition of lipid occurs [ 3].

During diabetes, a profound alteration in the concentration and composition of lipids occurs.

Electrophysiological analyses revealed a profound alteration of oscillatory activity in the CA3 region of the hippocampus.