Exact(2)
The present study analyzed the gene expression profiles and pathways that may be involved in the progression of neuro-AIDS in patients with or without apparent features of HIVE-induced dementia by using a comprehensive bioinformatics analysis.
The RNA samples were collected from whole blood for 50 TPM- and 49 placebo-treated participants at three time points: baseline and the ends of weeks 8 and 12. Genome-wide expression profiles and pathways of the two groups were compared for the responders and non-responders at Weeks 8 and 12.
Similar(58)
Our modeling algorithm integrates high-throughput drug response profiles and pathway information from signaling databases.
Results demonstrate common and specific DEP profiles and pathway networks among four NFPA subtypes and for the first time reveal NFPA-proteome heterogeneity.
Gene expression profiles and pathway analysis can be used to define candidates for targeted proteomics [ 26] discovery and improve identification sensitivity of expressed proteins.
Users can search this database to identify transcript abundance profiles and pathway information using five query pages (Gene Search, Pathway Search, Differentially Expressed Genes (DEGs) Search, Gene Group Analysis, and Co-expression Analysis).
To identify differential gene expression profiles and pathway associated with AHL, we performed microarray analysis using Illumina MouseRef-8 v2 Expression BeadChip and pathway-focused PCR array in the cochlear tissues of Cmah-null mouse.
(14) As these relationships become better understood, one can begin to make computational predictions about what species will be made based on gene expression profiles and pathway maps, 448) and even predictions about glycan structures from genomic information about glycosyltransferases, although the outcomes still require experimental verification.
Similar values were obtained in GFP-HX1 (8.3% and 66.1%) and 88GFP-HX1 cells (8.6% and 65.4%) (Fig. 4), which indicates that the VP88GFP expression does not alter the cell death profile and pathways.
Pattern recognition methods including principal components analysis (PCA), partial least-squared discriminant analysis (PLS-DA), orthogonal partial least-squared discriminant analysis (OPLS-DA) and computational system analysis were integrated to obtain comprehensive metabonomic profiling and pathways of the biological data sets.
Gene expression profiling and pathway analysis followed by pharmacological screening identified activated ERK and JNK signaling as key drivers of neurodegeneration in mutant SOD1 MNs.
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