In line with the cytokine profiles, sensitization with OVA in the presence of GO stimulated the production of OVA-specific IgG2a and down-regulated the levels of IgE and IgG1.
Several hundred allergens have been cloned and expressed as recombinant proteins, and these provide the means for making a very detailed diagnosis of a patient's sensitization profile.
We observed an infection cycle-dependent sensitization profile of infected cells for apoptotic stimuli.
We concluded that during the transformation process, SV40EReg provides a cellular and molecular context that synergizes with the senescent secretory profile to promote sensitization toward TRAIL.
To determine the allergen sensitization profile, 206 individuals born in Singapore were screened for responses to the 12 most common allergens reported to be present in the tropical environment.
Indeed, the sensitization profile was strikingly similar to that seen in the Δ tarO strains, although the sensitivity was generally higher in the deletion strain, likely because it was completely devoid of WTA (as shown by phosphate analysis in Supplementary Table 1).
The so-called component-resolved immunotherapy of allergies proposes an immunization tailored to the molecular sensitization profiles of individual patients.
We aimed to investigate sensitization profiles of egg allergic patients and compare in vitro IgE reactivities of eggs from ancient chicken breeds (Araucana and Maran) with those from conventional laying hen hybrids.
Comparable results were shown by Vereda et al., who investigated the sensitization profiles of Spanish children and adolescents with peanut allergy [ 19].
Different sensitization profiles between gemcitabine and carboplatin and ATR kinase inhibitor ETP-46464 and Chk1 kinase inhibitor UCN-01 were observed and this should be considered in the rationale for Phase I clinical trial design with ATR kinase inhibitors.
