Sentence examples for profile essential from inspiring English sources

This observation echoes those recently reported in adult glioma tissues [52] and in adult glioblastoma-derived TSCs [49], [53], and lends credence to the view that brain TSCs could be characterized by the unique association of a neural stem cell profile and of a mesenchymal profile essential for maintaining the tumor initiating properties of the cells [49].

These data suggest that Smad4 is required to establish the transcriptional profile essential for proper CD8+ T-cell differentiation.

Our study indicates that putative BT-ICs enriched in a mammosphere assay have a distinct miRNA profile, essential for their proliferation balance.

This analysis demonstrated that trabectedin is a feasible treatment in young and elderly patients with STS, with meaningful clinical benefits and an acceptable safety profile, essential in palliative treatment of elderly patients.

Silva, J. M. et al. Profiling essential genes in human mammary cells by multiplex RNAi screening.

Sport Profiles: Essential for multisport and triathletes, this feature enables users to quickly switch between sports during training.

Moreover, our results uncover a novel role for Tip60 HAT activity in controlling neuronal specific gene expression profiles essential for nervous system function as well as a central regulatory role for Tip60 HAT function in general metabolism.

However, despite the undisputed central role that Tip60 plays in the regulation of general developmental gene control, the question of whether the epigenetic HAT activity of Tip60 is required for differential tissue-specific gene expression profiles essential for organismal development remains to be explored.

Native atrial and ventricular CMs exhibit distinct molecular and functional profiles essential for their diverse physiological roles in the heart, and hPSC-CM cultures enriched in these subtypes would have significant added value in drug response assays.

Increasing treatment options in endometrial cancer make accurate histopathological categorisation and molecular profiling essential, although predictive factors related to the EGFR/PI3K pathways have not been validated sufficiently for routine use.

Gaining a high profile is essential for any patient representative group, to stop doctors patronising them.