Sentence examples for proficient lines from inspiring English sources

Moreover, experiments introducing a transgenic reporter gene into cancer cell lines revealed that expression of the reporter was associated with genetic instability: upon introduction of the transgene, cell lines deficient in MMR showed strong repression of the reporter gene compared to MMR proficient lines (Lengauer et al. 1997).

Also released were the future justice's meticulous notes from law school, which he kept in handsome hardbound volumes and sometimes illustrated with proficient line drawings, and a journal he had kept off and on starting in 1947.

MDA-MB231 cells were chosen as a caspase-proficient line.

In agreement with 32Hc activity requirement for DNA-PKcs kinase, we found that DNA-PKcs proficient cell lines M059K and F18 were radiosensitized by transfection with 32Hc while DNA-PKcs deficient cell lines M059J, KA4 and V3 were not (Supplementary Fig. S2B).

Moreover, IGF-1R inhibitors were added on HR proficient cell lines to assess mRNA and protein expression of RAD51 by qPCR and western blot.

Our analysis revealed that steady-state levels of cAMP are maintained very low in both FH-deficient and proficient cell lines.

We also analysed the expression of the oxidative damage enzymes MutYH (MYH), 8-oxoguanine glycosylase (OGG1) and MTH1 in MSH2 deficient and proficient cell lines (Fig S2D of Supporting Information).

In contrast and as expected, the SW480 MMR proficient cell line was sensitive to the cytotoxic effects of MNNG since it possesses a functional MMR system.

ALBANY, Aug. 15 — A proficient offensive line has been compared to a clenched fist, its five pieces working together to deliver one fierce blow.

Mutation rates from hMSH3−/− and MMR-proficient cell lines were not calculated due to a lack of net fluorescent M2 populations.

We further show that the HER-2 specific CTLs induced cytotoxicity, in synergy with trastuzumab, specifically depends on an intact APM, in view of the fact that down-regulation of TAP-2 expression in the TAP-2 proficient cell line OE33 hinders the synergistic cytotoxic effect induced by CTLs and trastuzumab.