Sentence examples for proficient expression from inspiring English sources
Interestingly, the apoptotic effect of 4-Me was significantly diminished in the Nox4-deficient MDA-MB-231 (MDA-MB-231 Nox4 siRNA) cells as compared with MDA-MB-231 control cells, indicating proficient expression of Nox4 is essential for the apoptosis-inducing effect of 4-Me.
S. aureus Newman is proficient in expression of α and δ toxin but deficient for β toxin due to the insertion of a prophage in hlb [63].
Although the majority of tumours carrying both FAK null alleles were proficient for FAK expression due to the lack of Cre expression, several neoplastic glands possessed areas of epithelial cells that maintained Cre expression and therefore lost FAK expression.
The protein O6-alkylguanine DNA alkyltransferase (Atase) is respO6-alkylguanine DNAalkyltransferasens generAtaseby several clisically imporesponsiblecancer drugs; this is maniforthes active repairance in thofe cancer cell lines proficient in Atase expression.
Overall, these studies support the hypothesis that balanced and proficient BER protein expression and BER capacity is required for genome stability and protection from hyperplasia and tumor formation.
Genetic and biochemical analyses revealed that the majority of these tumours had escaped Cre-mediated recombination of the conditional FAK alleles and were proficient for FAK expression, indicating a strong selection for retention of FAK signaling.
In contrast, mit− mutants are proficient in mitochondrial gene expression, although these yeasts are also unable to respire.
If the transformant colonies on MacConkey plates were all pale-coloured, the ZFR was deemed to be a recombination-proficient mutant, so the expression plasmid was isolated and the ZFR reading frame was sequenced.
As cisplatin caused decreased cell viability in the MLH1-proficient cells tested, the expression of apoptotic- and anti-apoptotic proteins was conducted in attached and detached cisplatin-treated cell lysates at doses that showed significant detached cells and decreased cell viability at 24 h (50 and 200 μ M) for A2780MNU1-MLH1 and OVCAR3.
These data support the hypothesis that balanced and proficient base excision repair protein expression and base excision repair capacity is required for genome stability and protection from hyperplasia and tumor formation.
To address this issue, we expressed viral antigens in tumors that are either deficient or proficient in TAP and MHC-I expression.
