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The alternative procedure included a search for interacting proteins for the gene products mapping to the candidate region.
We further postulated a possible role of erythrocyte membrane stability and altered erythrocyte lifespan (ANK1, SPTA1) and hemoglobin deglycation (FN3K) based on the known function of the respective gene products mapping to the vicinity of the association signals.
Interestingly, the networks showed overlap with both arsenic and cadmium-associated gene products mapping to common pathways including the p38 mitogen-activated protein kinase (p38 MAPK) and hepatocyte nuclear factor 4 (HNF-4) pathways (see Additional File 4: Metal modulated sub-networks).
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In the latest version of Apple's iPhone software, which became available Wednesday, Apple removed two mainstay apps, both Google products — Maps and YouTube.
"We don't have the specific products mapped out yet".
As part of this new initiative, Google is combining the 18 individual Maps APIs the company currently offers into only three core products: Maps, Routes and Places.
The percentage of signature gene products mapped in this dataset ranged between 40 and 85.
The resulting set of PPIs contained 28,629 non-self-interacting, non-redundant interactions between 8,495 proteins, of which 132 were cardiovascular targets and 191 were cardiovascular gene products mapped by Gene names.
"It was part of his ambassadorial role, signed off at board level, that we had a road map and product map to follow.
The product map is now often more complex and more expensive to create than trying to figure it out as you go.
The product map follows the journey from the cotton fields (the raw material) through collection, looms and weaving, dyeing etc until the T-shirt is on the store shelf.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com