Additionally, the impact of several design parameters on the process performance in terms of purity, yield, productivity and buffer consumption is discussed.
Based on the actual refolding data, we compared throughput, productivity, and buffer consumption between two batch dilution refolding processes – one using urea for IB dissolution, the other one using NaOH for IB dissolution – and our continuous refolding process.
Performance was evaluated in terms of productivity, yield, and buffer consumption.
For example, α-lactalbumin refolding with ultrafiltration achieved several-fold higher productivity and lower buffer consumption compared to refolding with the batch dilution method.
Simulated moving bed (SMB) technology is a continuous chromatographic technique proven to have many advantages compared to conventional batch chromatography, such as: raised productivity and product concentration, reduced buffer consumption as well as more efficient use of raw material.
There may no longer be virgin lands to be settled and cultivated, as in the 19th century, but there is no reason to believe that agricultural productivity has hit a buffer.
Productivity was lower than in buffer but product yield was higher because of the much lower relative hydrolysis rates.
We devised a health derivative in a sense, a sort of insurance contract that an investment firm could sell to mining companies to buffer them against the potential productivity losses due to HIV.
Build recreational areas into your workspace and organize fun events with the purpose of leveraging humor to buffer stress and increase morale, productivity and persistence.
The purpose of this study was to determine the effects of bioretention facilities and buffer strips on environmental quality with productivity and resources as constraints.
