Sentence examples for productive initiation from inspiring English sources

Both the freed eIF4E and polymerized PABP associate with eIF4G in a productive initiation complex), beginning the synthesis of Cyclin B and driving meiotic maturation.

However, transcription initiation is a dynamic process and the release of at least a portion of the TFIID-promoter DNA contacts has been shown to be a critical step for productive initiation (Yakovchuk et al., 2010).

Nascent transcription analysis demonstrated that the ΨCTD is required specifically for productive transcription initiation, as an RNAP-II severely truncated within the ΨCTD caused abortive initiation.

Anderson and Kedersha [54] proposed that mRNAs in stress granules are subjected to triage: first they are monitored for integrity and composition, and then they are sorted for productive translational initiation or targeted to degradation.

Importantly, all the undocumented-uninsured patients continued to work and were productive, after initiation of RRT.

Surprisingly, TFIIB serine 65 phosphorylation is required after the phosphorylation of serine 5 of RNA pol II C-terminal domain (CTD) has occurred, but before productive transcription initiation begins.

It has been proposed that DnaA first binds to a few high affinity DnaA boxes followed by binding to low affinity DnaA boxes to form a productive DnaA oriC initiation complex [23].

Initiation of productive infection was less efficient when TG neurons were infected with HSV-1, but still resulted in 12% of the neurons with axonal outgrowth in the outer chamber being positive for the late HSV-1 antigen gD at 48hpi (Fig. 1F).

Promoter escape is the transition from initiation to productive elongation, which may involve multiple reinitiation events (abortive initiation).

These approaches generated detailed maps of Pol II nascent transcription in mammals and flies, which accumulates at promoters, providing a regulated transition from initiation into productive elongation (Adelman and Lis, 2012; Core and Lis, 2008; Gilchrist et al., 2010; Rahl et al., 2010).

A key question is whether the deficits in reactivation observed for ICP0 mutants represent a failure to initiate exit from latency or failure to enter productive cycle replication following the initiation of reactivation.