Exact(5)
This means that only the "productive" events of transcription are considered.
According to productive events the median elongating RNA pol II density of 0.078 molecules/kb corresponds to an average of 0.096 molecules/gene.
A merit of the single-molecule approach is that we could characterize these rare productive events (e.g., Figure 2B C) independently of the excess of non-productive events.
In the productive events, Arp2/3 complex and diVCA release were not simultaneous.
Metivier and colleagues postulate that transcriptionally productive cycles are rather slow, because the initiation of transcription requires specific sequences of events to occur, which are ordered, kinetic, and directional and dependent on productive events that occur frequently from many rapid, stochastic, transient, and unproductive associations of factors (Metivier et al. 2006).
Similar(55)
So do yourself a favor and sign up for Disrupt SF today so you can get on the CrunchMatch bandwagon and get ready for a most productive event experience!
For elementary school teachers, a parent conference is a normal and often productive event.
As a young adult, K believes that divorce can be a healthy and productive event for a family.
Altogether, these relationships lead us to ask whether calpain cleavage of SMN is a physiologically productive event, leading to proper SMN function, versus a pathological result of aberrant calpain activation.
We have developed an improvement to ribosome profiling, which we term Poly-Ribo-Seq, to ensure that footprinted mRNA sequences represent regions of active translation rather than non-productive events.
Assuming that the 4670 genes, from which we obtained TR data, are representative of the 5796 non dubious ORF-containing genes, it is possible to calculate approximately 1000 productive transcription events (leading to the production of new mature mRNAs) occurring each minute in a yeast cell.
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