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Macrophage secretion is inhibited by the production of migration inhibitory factor [ 10].
The secretions-induced production of chemotactic factor MCP-1 and decreased production of migration inhibitor MIF by monocytes did not increase migration, indicating that secretions inhibited migration independently of the levels of these chemokines; participation of MIP-1β inhibition cannot be ruled out.
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This paper proposes a double modelling approach to such migrations, first in terms of a cognitive model of the production of migrations, and second in terms of a mathematical safety analysis of severity and consequences.
This result supports a household production model of migration where migrants may be temporary by choice and not because of legal restrictions or even a bad experience in the labor market.
Cell density, surface contact, and physiological signals all provide critical stimuli, and close cell alignment and the production of secreted migration factors facilitate mass translocation [31].
This counteracting effect of NMPF paralleled the downregulation of the effects of LPS on the production of macrophage migration inhibitory factor (MIF) by spleen cells, on the plasma level of liver aminotransferase, and on the expression of several splenic lymphocyte and macrophage surface markers.
Additionally, lipid infusion in humans acutely activates NFκB, a proinflammatory transcription factor, and stimulates the production of macrophage migration inhibitory factor and reactive oxygen species in circulating mononuclear leukocytes [ 17].
Aiming to analyze the importance of the antibodies to the elimination of bacteria, the response is represented firstly by the simulation of only the innate cells (Case 2) and then with the complete model including activation of the lymphocytes, production, and migration of antibodies to the tissue (Case 3).
Many countries lack the human resources needed to deliver essential health interventions for a number of reasons, including limited production capacity, migration of health workers within and across countries, poor mix of skills and demographic imbalances.
Several pro-inflammatory properties have been described for the S100A8/A9 complex, such as activation of monocytes [ 29], amplification of cytokine production [ 30], regulation of migration of myeloid derived suppressor cells [ 31] and, as demonstrated recently, a ligand for receptor for advanced glycation end products (RAGE) and TLR4 [ 32].
Targeted ablation of the different subsets reveals that the very first dbx1-expressing progenitors are critically required for the survival of anterior neural tissues, the production and/or migration of cephalic neural crest cells and, ultimately, forebrain formation.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com