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"Central prostaglandins work only through this one receptor" to promote pain sensitization, says pain expert Clifford Woolf of Harvard's Massachusetts General Hospital in Boston.That also means that aspirin and other so-called nonsteroidal anti-inflammatory painkillers, which block prostaglandin production, exert their effects in the spinal cord, not just in peripheral tissues, as was once thought.
Normally, eNOS phosphorylation and subsequent NO production exert anti-apoptotic and anti-oxidative effects in I/R hearts [ 44, 45].
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Even if time has weakened Shawn's thesis, Dominic Cooke's production exerts a strong grip.
The production exerted an enormous influence on American show business by introducing jazz dancing to Broadway; launching the careers of Florence Mills, Josephine Baker, and many other dancers and singers; and opening doors to further efforts by African American pianist-composers such as James P. Johnson and Fats Waller.
Increased agricultural production exerts a negative pressure on the environment, particularly regarding the use of agricultural waste.
Here, we tested whether Bifidobacterium adolescentis IM38, which inhibited nuclear factor kappa B (NF-κB) activation in Caco-2 cells and peritoneal macrophages and inhibited Escherichia coli LPS production, exerted an anticolitic effect in mice with HFD-induced obesity.
Additionally, Rho et al. [ 31] demonstrated that the position and the number of sugar moieties affect the suppression of NO production exerted by flavonol glycosides.
In advanced CKD, FGF23 no longer maintains phosphate homeostasis and the suppression of 1,25(OH ₂D production exerted by FGF23 induces PTH elevation, resulting in secondary hyperparathyroidism (SHPT).
For instance, up-regulation of YeaP (a diguanylate cyclase that positively regulates the expression of csg genes involved in curli and cellulose production) exerted a negative effect on glycogen accumulation (Fig. 1 ).
As a consequence, pharmacological QC inhibition should reduce pE-Aβ production and exert beneficial effects on these neuronal populations.
Tregs depletion enhanced anti-tumor CD4 responses by increasing IFN-γ production, which exerts a potent anti-angiogenesis function.
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