Sentence examples for production aggregation from inspiring English sources

Most current Alzheimer's disease (AD) therapies in advanced phases of development target amyloid β-peptide (Aβ) production, aggregation, or accumulation.

So a series of explorations focusing on physiological and pathological processes that participate in the production, aggregation, and clearance of A β have been widely studied.

Over the last decade, several classes of drugs aimed at altering Aβ production, aggregation or degradation/clearance have been clinically tested.

Many new candidate drugs are targeting the production, aggregation, or clearance of Aβ such as γ-secretase inhibitors [ 14, 15] and β-secretase inhibitors [ 16- 18].

Supportive care, defined as not including treatments that affected platelet production, aggregation, activation, granulocyte-macrophage colony-stimulating factors, or any other investigranulocyte-macrophage colony-stimulatinghe study.

The genetics of late-onset AD is complex, although several of the common risk alleles other than APOE are involved in production, aggregation and removal of Aβ [ 33].

Studies also suggest that increased extracellular and capsular polysaccharides production facilitate aggregation of A. brasilense cells in high C/N ratio medium (Burdman et al. 1998, 2000; Bahat-Samet et al. 2004).

Applying a DoE (Design of Experiments) approach, a fractional factorial design was used to systematically evaluate the influence of cultivation temperature and pH as well as their synergistic effect on cell growth as well as on recombinant protein production and aggregation.

Exactly how disturbances of production and aggregation of the beta-amyloid peptide gives rise to the pathology of AD is not known.

So if we had a complete understanding of the molecular mechanisms involved in the production and aggregation of the relevant misfolded brain proteins, we would probably have a good shot at preventing AD altogether -- in addition to preventing a half dozen other important neurodegenerative diseases.

These clones were cultured in VGB6 and/or KOSR+2i media for at least three passages followed by the production of aggregation chimeras.