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Even with high quanta producing diseases, such as measles, where improved ventilation might be beneficial, reducing: (i) waiting times; and (ii) the number of susceptible individuals present, appear to be as important as installing expensive ventilation/air cleaning equipment.
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Organisms capable of producing disease are pathogens.
In recent months, researchers have discovered that a prion from hamsters, thought never to infect mice, not only replicates profusely in mice but it does so without producing disease symptoms.
As a result, these engineered miRNA-regulated viruses elicited strong protective immunity in mice without producing disease.
Here we discuss strategies involved in producing disease-resistant crops and examples of genetically engineered crops against bacterial and fungal pathogens.
We were interested in clarifying how HSV-2 0ΔNLS consistently replicated in mouse eyes without producing disease.
However, much less attention has been paid to bacterial carriage populations, which inhabit hosts without producing disease.
NF-κB has rightly been called a double edged sword, both needed by the body in its defense and producing disease when inappropriately activated.
There has been a great deal of interest in producing disease-resistant transgenic plants that express chitinases.
Third, limiting replication of the virus in mammalian cells enables vaccination with a live virus without producing disease.
The variable penetrance also raises the possibility that C9ORF72 expansions may be a risk factor for disease and may not be capable of producing disease in isolation.
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