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Organisms capable of producing disease are pathogens.
In recent months, researchers have discovered that a prion from hamsters, thought never to infect mice, not only replicates profusely in mice but it does so without producing disease symptoms.
In certain cases, adaptation is so close that the parasite is unable to infect any other hosts under natural conditions; this is true of many microorganisms producing disease in humans.
As a result, these engineered miRNA-regulated viruses elicited strong protective immunity in mice without producing disease.
However, much less attention has been paid to bacterial carriage populations, which inhabit hosts without producing disease.
We were interested in clarifying how HSV-2 0ΔNLS consistently replicated in mouse eyes without producing disease.
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Here we discuss strategies involved in producing disease-resistant crops and examples of genetically engineered crops against bacterial and fungal pathogens.
There has been a great deal of interest in producing disease-resistant transgenic plants that express chitinases.
Scientists also do not know precisely how the virus is transmitted or how it produces disease in animals and humans.
Excessive intake of certain vitamins, especially vitamins A and D, can also produce disease.
The agents used for immunization should not in themselves produce disease.
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