Unless this change produces drastically improved results, there is a solid chance that Fisher – slipping toward a fourth consecutive losing season in St Louis – will be losing his own job at the end of this year.
We found that Rgs2−/− MDSCs isolated from tumors produce drastically reduced levels of MCP-1 compared to wild type.
However, substitutions at this position produce drastically different catalytic outcomes.
Interestingly, TH can produce drastically different responses in different animal groups [ 24, 33].
The formation of partial interpenetrating network in the interface of nanofibers/matrix produces drastically powerful interfacial linking force which functions mainly in the enhancement of composites.
However, as a consequence of variation in the strength of sexual selection the testis not only has to produce drastically different numbers of cells, but also cells of highly variable morphology and complexity.
Furthermore, we show that the WF and Moran models may produce drastically different MPs for a finite population, and that this difference grows with the number of loci and mutation rates.
ATG16L1-deficient macrophages from chimeric mice (lethally irradiated mice with haematopoietic reconstitution from ATG16L1-deficient foetal liver cells) produce drastically elevated levels of the inflammatory cytokines interleukin-1β and-18 (86).
Reviewer 1: Patrick Forterre (Institut Pasteur) Pandoraviruses are fascinating new organisms, which illustrates the capacity of viruses to produce drastically different types of virions, with strikingly different structures and genomes encoding from 2 genes up to 2500 genes [ 1].
Gene expression profiling in a pancreatic beta cell model treated with glucose and cAMP has shown that the majority of genes regulated in sustained treated cells were not regulated by transient (1 h) treatment, indicating that beta cells can produce drastically different transcriptional outputs in response to different durations of metabolic stimuli [ 2].
