In several cases, choice of LD cutoff influences significance due to information loss, whereas the weighted method produces a significant p-value.
In only 5 of the 1,000 simulation runs did the Gene Wiki-enhanced annotation set produce a significant P value (p < 0.01) when the PubMed-only set did not.
In a second approach, and in agreement the to statistical significance of the functional analysis (notably, all GOA terms presented in Table 1 produced a very significant P-value), we added a new layer of information by using the cancer-related functions extracted from GOA.
*denotes a significant p value.
* indicates a significant p value.
For 'politics', this fact produced the marginally significant p-value, which might have been statistically significant with a larger sample size of course participants (GH-yes).
We record how many times (out of 500) each of the methods produces significant P-value (P < 0.05), which measures the false-positive rate of each method.
An initial Pearson's Chi Square test, with the three years and the number of students who passed or failed, produced a significant value of p = 0.049 indicating that a significant statistical difference exists.
Due to our large sample size, all of the hypothesis tests produced statistically significant p-values.
In a large pool, even small differences will easily produce statistically significant p-values.
