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calcNormFactors, estimateCommonDisp, estimateTagwiseDisp, and exactTest were used with default parameter, when processing the MCF-7 replicates.

Smaller isolated voids were by default removed by the noise filter in processing the images.

Processing the rest.

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Previous resting state (RS) functional magnetic resonance imaging (fMRI) studies in adult patients with migraine have demonstrated abnormal functional connectivity (FC) of brain networks involved in pain processing, including the default mode (DMN), the salience (SN) and the executive control (ECN) network.

In the non-default setting of the CRISP program which involves the selection of the maximal circular area for further image processing, the automatic (default) reciprocal basis vector assignment function sufficed to arrive at qualitative correct results for image #7, see Tables 4 and 6.

Image pre-processing used the default settings involving intra-subject realignment, bias correction, segmentation, and normalization.

If the dataset is of sufficient quality for quantification, it is recommended that after pre-processing, to use the default parameter set of a processing pipeline be used to yield an initial segmentation.

'MP calculation' was applied for post-processing the networks, the characters were equally weighted, and the other median-joining parameters followed the software default.

Aside from the default processing options in FTK, additional refinements were selected to carve different types of data and parse complex information.

This early polarity in expression contributes to the subsequent posterior localized expression of Shh, and this morphogen in turn reinforces the anteriorly restricted Gli3 protein activity (Shh inhibits the default processing of the Gli3 protein to its repressor form (Gli3R), thus, creating a gradient of Gli3R along the AP axis) (Wang et al., 2000).

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