Sentence examples for processing of this miRNA from inspiring English sources

We also analyzed processing of this miRNA in Hela and NIH 3T3 cells, and in both cases were unable to detect knockdown of the complementary target.

We found that this substitution was associated with low levels of mature miR-16 production, revealing a functional impact on the processing of this miRNA.

This could be explained by the fact that: (i) the pre-miRNA is very stable; (ii) the processing rate of this miRNA from pri/pre form to mature miRNA is slow which means that most of the miRNA is left in its pri/pre form.

These ml-sRNAs are in phase with the canonical miRNAs, suggesting that they are produced during phased processing of the miRNA precursor RNAs by DCL1 [58].

Expression of the miRNAs from their native genomic background ensures the physiological processing of the miRNA.

Despite overexpressing other ADAR proteins with dsRNA-binding domains, they did not radically inhibit processing of this pri-miRNA by Drosha.

It is not clear how the 3' processing of these miRNAs occurs, but it may involve premature termination of transcription.

All are expressed from their genomic backbone, ensuring physiological processing of the miRNAs.

Processing of miRNA precursors into mature miRNA's is catalyzed by the RNA processing enzyme Dicer [ 4, 5].

Although the mechanism is unknown, this observation is consistent with previous results suggesting that processing of miRNA precursors to mature miRNAs can be rapidly induced by synaptic activity.

Quantitative Northern blot analyses were used to determine the level of mature miRNA expression and processing of the pre-miRNA and mature miRNA.