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The amount of correctly processed and functional p.Phe508del-CFTR protein is increased by efficient CFTR gene transcription, processing of the primary transcript by splicing and subsequent biosynthesis of the membrane protein in the ER.
Studies of the biogenesis of microRNAs have revealed that the earliest steps of processing of the primary microRNA transcript occur preferentially before release from the chromatin template.
These isoforms originated from skipping events during the processing of the primary transcripts.
These bands indicate endonucleolytic processing of the primary transcripts into smaller fragments.
We tested the alternative possibility that there may instead be measurable changes in the processing of the primary transcript.
The randomisation code will be hidden from research assistants during assessments and data processing of the primary and secondary outcomes.
Similar(33)
These cells convert the sound vibrations to nerve impulses in the fibres of the cochlear nerve, which transmits them to the brain stem, from which they are relayed, after extensive processing, to the primary auditory area of the cerebral cortex, the ultimate centre of the brain for hearing.
The influence of several formulation and processing parameters of the primary emulsion was studied accordingly.
In a dual task, participants perform two tasks concurrently with a secondary reaction time (RT) task sensitive to cognitive processing demands of the primary task.
Subjects always responded first to the primary task and subsequently to the secondary task, ensuring that attentional resources were manipulated by the processing requirements of the primary task and not by the number of items in the secondary task.
RNA species transcribed from the sRkC locus could result from 5' and 3' end processing events of the primary 211/218 nt long transcripts resulting in precise 5' monophosphorylated ends and variable 3' ends.
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CEO of Professional Science Editing for Scientists @ prosciediting.com