Sentence examples for processing of miRNA from inspiring English sources

The 3'-end variants may thus arise from preferential degradation at the 3' end or from imprecise processing of miRNA precursors by Dicer, thereby generating miRNAs with differing 3' ends [ 36, 37].

ADAR-dependent editing can control targeting specificity and the stability and processing of miRNA precursor transcripts [30], [31], [32].

Future studies are necessary to determine if alternative and tissue-specific DCL processing of miRNA precursors also occur during C. sativus miRNA biogenesis.

Alternatively, DCR-1 may be more often bound to the abundant miRNA precursors, and RDE-4 functions to divert DCR-1 from the processing of miRNA precursors to the processing of long dsRNA.

(B) "Loop-first" processing of miRNA hairpins.

(A) "Possible loop-last" processing of miRNA hairpins.

Therefore, ongoing analysis of the cause of reduced AGO2 expression in melanoma cells could lead to insights into fundamental process of RNase III free processing of miRNAs.

Although miRNAs regulate many cellular processes, often targeting multiple genes, the processing of miRNAs to maturity is thought to be controlled by a smaller subset of genes.

The fold difference between mature and pre-miRNAs varies greatly among the miRNAs tested suggesting that processing of miRNAs in HeLa cells fluctuate significantly between different miRNAs allowing accumulation at different maturation stages.

Several studies revealed that SNPs in miRNA genes could affect, either increase or disrupt the processing of miRNAs.

In addition we have identified two hnRNPs whose expression levels differentially alter the processing of miRNAs.