Numerous characterized ncRNAs function via base pairing with target RNA sequences to direct their biological activities, which include critical roles in RNA processing, modification, turnover, and translation.
Someone needed claims processing modification from the prosecution to the defense side of the legal trade, and the original developer stalled the client for six months, and said it would take them six months beyond that to make the conversion.
Ribosomal subunit assembly in vivo is a highly complex process, which composes of a large number of intertwined ribosomal protein (RP) binding and rRNA maturation (rRNA folding, processing, modification and assembly) events.
Indeed Tortosa and colleagues reported that co-expression of comQ and comX in E. coli leads to the production of active pheromone in the medium, demonstrating that ComQ is the only dedicated protein required for processing, modification, and release of active ComX pheromone (Tortosa et al. 2001).
Accordingly, individual proteins or subcomplexes were suggested to participate in steps that trigger processing, modification and folding of pre-rRNA, assembly of ribosomal proteins and/or export through the nuclear pore (see [2] for a recent review).
Final protein levels are further affected by control of translation, and control of protein processing, modification and degradation [ 15].
In the category transcription the putative and known function of the corresponding genes that are up-regulated is in RNA synthesis, processing, modification and in ribosomal RNA synthesis, processing, and modification.
RNA binding proteins control gene expression programs in living cells by regulating RNA processing, modification, localization, translation, and turnover (Glisovic et al., 2008).
Therefore, efficient production of ribosome subunits requires the coordination of rRNA and rprotein transcription by different RNA polymerases, rprotein mRNA export and translation, and rprotein import and nucleolar targeting, as well as rRNA processing, modification, and protein assembly.
Data requests that relied on post-coordinated clinical concepts, aggregate values of clinical findings, or temporal conditions in their inclusion/exclusion criteria could not be fulfilled using the i2b2 hive alone, and required one or more intermediate data steps in the form of pre- or post-processing, modifications to the hive metadata, etc.
