While the focus of BRCA1 investigation has been on DSB processing, its potential role in dealing with replication stress is relatively less explored.
Current research regarding the pathogenesis of tension type headache is focused on altered nociceptive pain processing and its role on chronification [5].
We will especially highlight quantitative regulation of 3′end processing and its role in human pathophysiology.
It is therefore likely that the reduction in EMG1 causes a delay in 45S to 18S rRNA processing via its role in RPS19 recruitment or rRNA folding rather than its catalytic activity.
We conclude that transgenic IgNrg1β1 strictly requires Bace1 processing to exert its role in muscle spindle formation.
The specialized DNA polymerase μ (pol μ) intervenes in the repair mechanism non-homologous end-joining (NHEJ) as an end-processing factor but its role has not been fully elucidated.
By reducing the levels of a transcription, elongation, or processing factor, we can examine its role in various transcriptional and co-transcriptional processes.
In addition a recent review article on the STS [19] discusses its role in processing the meaning of biologically relevant signals (i.e. eye movements, body movements, lip and mouth movements).
TACE has been implicated in RA due to its role in processing membrane-bound TNF to its soluble form [ 37].
