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SPM5 (http://www.fil.ion.ucl.ac.uk/spm) was used for all pre-processing and statistical analyses of scans.

For spatial pre-processing and statistical analyses of the functional MR data, the statistical parametric mapping software package (SPM5, Wellcome Department of Cognitive Neurology, London, UK) was used.

Pre-processing analyses and statistical analyses of quantitative sensory testing data will be performed according to the protocol used by Rolke et al. [ 63].

We applied an image processing analysis, a clustering analysis method and statistical analyses of intensity readouts to detect host factors involved in HCV infection.

Due to the haphazard selection of animals, we do not know the family of origin of selected fish (but see Data processing and statistical analyses, below).

Cortical thickness was automatically measured across the cortical mantle, and data processing and statistical analyses were optimized for reliable detection of longitudinal changes.

ZA participated in planning of the statistical analyses and performed record linkages, data processing and statistical analyses.

Signal processing and statistical analyses were adjusted for storage time as explained below.

Data processing and statistical analyses were performed using Statistical Package for the Social Sciences (SPSS) version 14.0.

All data processing and statistical analyses were conducted using SAS version 9 (SAS Institute, Cary, NC).

By putting major emphasis on sample acquisition, handling, processing, MS signal processing and statistical analyses more robust and reproducible results can be achieved [18], [20], [21].

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