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It can be argued that since UCEs are often associated with genes involved in RNA processing and developmental tasks, especially these genes are dosage-sensitive and hence, a heterozygous deletion/duplication including such a gene will more likely result in disease.
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Sequence-specific transcription factors are responsible for processing environmental and developmental signals, and initiating the appropriate cellular response.
This will help disentangle further how word processing strategies and developmental constraints contribute to reduced activation of "embodied" category representations for printed words in childhood.
The molecular mechanisms underlying PST and migration are poorly understood although it is likely to involve changes in gene expression and gene function in regions of the body involved in processing environmental and developmental cues, such as the hypothalamus, pituitary and olfactory epithelium (Prunet et al. 1989; Nevitt and Dittman 1998; Falcón et al. 2007; Nordgarden et al. 2007).
Among these, SOX4, STAT3 and STAT5B are known regulators of metastatic prostate cancer through the regulation of genes involved in miRNA processing, transcriptional regulation, and developmental pathways [ 50- 52].
Recently, studies on developmental dyscalculia concentrated on basic numerical processing and found those with developmental dyscalculia exhibited an atypical effect; size congruency [ 10, 11] magnitude comparisons [ 5, 12] and subitizing [ 13].
Members of the plant AP family have been implicated in various physiological and developmental processes, including protein processing and degradation, senescence, stress response, programmed cell death and reproduction.
In the HS wood (low MFA), genes involved in translational elongation, transport (ion, electron and cation), stress responses and ribonucleotide biosynthetic process were more highly transcribed; whereas LS wood with high MFA had increased transcription of genes involved in different metabolic and developmental processes and RNA processing.
We propose that myogenesis-associated 5-mC and 5-hmC CpG sites help positively or negatively regulate transcription or co-transcriptional posttranscriptional RNA processing depending on the sequence and developmental context.
These subsets of genes represent the most active metabolic processes occurring in B. rapa developing seeds, such as photosynthesis, hormonal regulation, stress tolerance, cell wall, lipid, phosphate, amino acid, protein, signal transduction, transport, secondary metabolites, developmental process, and RNA processing and regulation of transcription (Additional file 7: Table S4).
Epigenetic regulation of gene expression is necessary for the correct processing of developmental programs and the maintenance of cell fates.
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