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To further evaluate the contribution of GSK3ß to vascular remodeling processes, we generated pcDNA 3.1 TOPO-cloning constructs carrying GSK3ß wild type (WT) cDNA and GSK3ß S9A (where serine at residue 9 is replaced to alanine) mutant.
To identify the patterns, if any, for these processes we generated graphics for a number of plates with large numbers of BACs with overlapping FPC locations (Fig. 6A).
In the present study, to develop a new effective therapeutic strategy for refractory PDAC, especially with regard to proliferation, tumorigenicity and invasion in metastatic processes, we generated hypoxia-resistant PDAC cell lines for reoxygenation experiments focusing on the Hh signaling pathway, and investigated the mechanism of the induction of malignant phenotypes by reoxygenation.
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To account for the levels of understanding of science and the evolutionary process, we generated two descriptive indexes (Science Index (SI), Evolution Index (EI)), analogous to RI (above).
During the ground motion simulation process, we generated 100 different M w = 7 earthquake scenarios and also used these scenarios for the sensitivity analysis.
To account for the levels of understanding of science and the evolutionary process, we generated two descriptive indexes (science index (SI), evolution index (EI); similar to Paz-y-Miño-C and Espinosa 2011a), analogous to RI (above).
To further test whether a single knockdown of AtPV42b impairs the reproductive process, we generated amiR-atpv42b-2 transgenic plants overexpressing another artificial microRNA targeting AtPV42b.
To determine the role of miR-203 in this process, we generated a KO mouse model.
To determine the functional importance of PD-1 in this tolerogenic process, we generated Tg4.PD-1−/− mice.
For each sequence processed, we generated 544 different smoothed profiles, corresponding to the 544 scales from AAindex.
As an initial step in understanding the role of RBP1 in this process, we generated a primary osteoblastic cell model in which RBP1 expression was reduced.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com