Dysregulation of these complex and precisely regulated processes underlies the pathogenesis of a wide array of neurological and psychiatric disorders.
The ability to measure biochemical and molecular processes underlies progress in breast cancer biology and treatment.
Since derangement of these physiological processes underlies the development/progression of heart failure, pharmacologic activation of SIRT1 and/or SIRT3 potentially ameliorates the disease.
Our aim was to investigate whether a more general lack of coordination among processes underlies dyslexic reading performance than would be suggested if the reading impairment were caused by a single deficient component part of the system.
The inability to coordinate these anorectal processes underlies the main pathophysiological abnormality in patients with DD. 23 These patients are thought to have impaired rectal contraction, paradoxical anal contraction, impaired relaxation, or a combination of these mechanisms.
Identification of mutations in specific genes associated with typical electrophysiological patterns and the comparison of these findings with those obtained from animal models may be the key factor in revealing how the failure of different molecular processes underlies the varieties of AN.
