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Loss of mitochondrial function due to calcium overload and inhibition of metabolism may render affected nerve processes unable to maintain plasma membrane integrity and thus cause collapse of nerve endings to the depth where the capsaicin exposure was insufficient to irreversibly overwhelm mitochondrial function (Fig. 4).
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Almost one year after Mr. Koizumi took office billing himself as a reformer, he seems overwhelmed by the process, unable to deliver.
In this case, the effect of working with the combined EDEO in the rate of 2,4-D degradation is negligible because the 2,4-D transport rate becomes comparable to the degradation rate, being the combined process unable to generate a concentration greater than that accounted in the single EO device.
The union itself would have been totally emasculated in the process, unable to protect its members.
Process unable to keep up with changing context.
On the other hand, although tumor cells arrest at some checkpoints in order to repair radiation-induced damage, it require growth factors to proceed effectively [ 24], therefore, inhibition of growth factor receptor make the process unable to facilitate repair, contributing to cell death.
As the tempo of new agent discovery accelerates, it is becoming increasingly clear that the current clinical trial process and its regulatory processes are unable to keep up.
If the presentations are too frequent the processes are unable to achieve their maximal effect.
If DNA repair processes are unable to rectify this DNA damage, it can ultimately lead to somatic mutations in breast cancer-related genes, an initiation step of carcinogenesis [ 2].
The depletion of ATP combined with elevated [Ca2+] and ROS leads to a gradual decline in cellular integrity as degradative enzyzmes are activated and ATP-dependent reprocessesesses are unable to operate [1,3,26,32].
It has had no genuine impact on the Arab-Israeli peace process, was unable to reunify the Palestinian movement and was widely seen in the region as complicit in Israel's siege on Hamas-controlled Gaza.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com