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This suggests that there is a cascade of biological processes that amplifies over time to lead to the phenotypic abnormalities.
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HIV-associated brain dysfunction is potentiated by a cascade of excitotoxic and apoptotic processes that amplify immunologic and inflammatory responses to the virus [ 87, 96, 99].
Stoichiometric symmetry should result from homologous recombination in the absence of processes that amplify or reduce the frequency of single products.
But polarization is not the cause, but the result, of a process that amplifies and extenuates conflicts.
In order to distill meaningful mechanical information from background noise, hair cells use an active process that amplifies and tunes their inputs.
The hearing of tetrapods including humans is enhanced by an active process that amplifies the mechanical inputs associated with sound, sharpens frequency selectivity, and compresses the range of responsiveness.
Thus, there is a process that amplifies the single-molecule, single-cell events into a disease that affects the whole organism.
By blocking the IL-1 receptor, the feed-forward process that amplifies the inflammatory cascade is attenuated thereby reducing microglial activation and reversing the behavioral abnormality after endotoxemia.
In contrast, IgM-RF sero-positivity is generally a somewhat later event, and it is primarily a reflection of an inflammatory process that amplifies the tissue injury already underway.
This method is time consuming and also increases the likelihood of false positive reactions due to cross-contamination. Nucleic acid sequence-based amplification (NASBA) is a single-step isothermal RNA-specific amplification process [ 23] that amplifies mRNA in a dsDNA background [ 24].
Nugen has designed a technique called Ribo-SPIA™, which is a three-step process that generates amplified cDNA from as little as 500 picograms of total RNA[ 21].
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