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Any network representation of biological processes suffers from the inherent limitations of the representation itself: just using nodes and edges of a limited number of types over-simplifies the complicated interplay of known (and unknown) biological processes that underlie a phenomenon such as cellular pluripotency.
Permeability in membrane filtration processes suffers from two major limiting factors: concentration polarization and membrane fouling.
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These processes suffer from incorrect protein folding, insufficient heme synthesis and heme incorporation.
Existing micro tool fabrication processes suffer from drawbacks such as surface cracks, residual stress and deformations.
Analytical solutions for two-dimensional Markov processes suffer from the state space explosion problem.
Typically, most drug development processes suffer from planning problems, as well as delays in development, unforeseen activities, cost overruns, and losses resulting from high turnover.
It is well known that such coating processes suffer from a severe drawback: weak adherence of the Au layer to the substrate.
Participatory scenario processes suffer from the reverse since they are able to tackle qualitative issues yet they lack the capacity for rigorous analysis of large numbers of interactions.
The inter-institutional post-acute stroke processes suffer from information discontinuity and information asymmetries between stakeholders in the healthcare service network (HSN).
Even initial movements towards supporting informal care processes suffer from the same issues: concerning a single standalone application or closed service, focusing on a particular aspect of care, e.g. a monitoring infrastructure for a specific condition or a "panic button".
Dye effluents from the textile industry represent a major environmental pollutant, and conventional degradation processes suffer from inefficiency, are not price competitive or result in toxic by-products [ 6- 9].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com