Sentence examples for processes of malignancy from inspiring English sources
These proteins participate in processes of malignancy progression and metastasis, such as oxidative stress, energy metabolism, cytoskeleton reorganisation, and signal transduction.
Furthermore, Src and EGF receptor reciprocally interact and appear to cooperate in the process of malignancy [ 5].
These results imply that during the process of malignancy there is not only cooperativity between Src and ErbB RTKs, but also selection for overexpression of a Src substrate that very likely has a role in tumour progression, probably by increasing the invasive or metastatic potential of breast tumour cells.
A striking feature of this PKA recognition motif is its strict conservation among the high-risk HPV E6 proteins and its absence in the low-risk HPV E6 proteins, suggesting that PKA-regulated degradation of hDlg is an essential function in the process of malignancy [ 46].
During the process of differentiation, malignancy may happen at any point.
We report here that KAI1 acts in the process of tumor malignancy and angiogenesis by profoundly suppressing metastasis via inhibition of CDCP1-enhanced Src activation and functional activation of VHL.
These novel findings may indicate that KAI1 functions as a profoundly effective metastasis suppressor in the process of tumor malignancy and angiogenesis through inhibition of CDCP1-mediated Src activation and a subsequent dramatic reduction in HIF-1α and VEGF expression via functional activation of VHL.
Evaluation of owner experience from performed RT may, especially when the procedure is newly introduced (e.g. in a country), together with the numerous available scientific reports of efficacy and morbidity, assist owners and veterinary surgeons in the decision-making process in case of malignancy.
In conclusion, our process of confirming malignancies started with the identification of possible cases reported at the time of a routine clinic visit.
In one patient, findings were consistent with inflammatory process in the absence of malignancy on surgical biopsy.
Our correlates and survival studies have shown that these two processes correlated with high grade of malignancy and with poor RFS.
