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Type XXII collagen could serve as a marker to explore pathologic processes of joint diseases and to study tissue junction formation during development and regeneration of cartilage due to its expression location.
This observation may reflect that these are structural elements only and do not directly modify the processes of joint destruction or repair.
Much of the evidence base focuses on the processes of joint commissioning and few studies have systematically studied the outcomes of this way of working.
These observations suggested that the aforementioned enzymes can be seen as candidate markers for the pathophysiological processes of joint inflammation and degradation.
Our data identify STR/Ort mice as a model of asymptomatic OA and highlight the novel and exciting putative utility of this model in identifying markers and processes of joint degeneration without the complicating factor of pain.
As exemplified in Fig. 2, in some cases (which will be described in more detail below), basic knowledge of the processes of joint development and homeostasis has driven subsequent steps in experimental research and revealed key factors associated with OA.
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The next research lesson will be given by another member of the group, with the same process of joint planning and review.
Figure 3 Process of joint RN selection, channel allocation and DyTSA scheme.
These days, she is exploring the process of joint degeneration that leads to osteoarthritis of the knee.
Understanding the details of ECM remodeling mechanisms in cartilage is critical for knowing the pathological process of joint diseases.
The process of joint closure involves roughness crushing and the adjustment of surfaces, and is strongly heterogeneous, orthotropic and nonlinear.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com