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Mechanical conditions have a significant influence on the biological processes of bone healing.
Bone regeneration approaches that mimic the natural processes of bone repair have generated significant attention.
The structure of living bone changes continuously due to the processes of bone remodeling and mineralization.
Thus, a cytokine network is established, which results in an imbalance of the processes of bone formation and bone resorption.
Details are provided for the macro and microscopic structure of bone tissue and the processes of bone growth, modeling and remodeling.
In orthodontic tooth movement, some cytokines released from periodontal ligament fibroblasts and alveolar bone osteoblasts on the pressure side can alter the normal processes of bone remodelling, resulting in physiological bone resorption.
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Both endochondral and intermembranous ossification produce immature bone, which undergoes a process of bone resorption and deposition called bone remodeling to produce mature bone.
The mechanical integrity of the bone-implant system is maintained by the process of bone remodeling.
For example, several research groups have investigated ways to mineralize collagen intrafibrillarly, in order to mimic the natural mineralization process of bone tissue13.
First, a brief summary of the physiological process of bone regeneration is outlined.
We expect that this device will help the process of bone regeneration.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com